腸内細菌とビフィズス菌に関する主な研究論文

  • Minami J et al, 「Lysozyme in breast milk is a selection factor for bifidobacterial colonisation in the infant intestine.」 Benef Microbes. 27:1-8 (2015)
  • Sugahara.H et al, 「Probiotic Bifidobacterium longum alters gut luminal metabolism through modification of the gut microbial community.」 Sci Rep 5: 13548 (2015)
  • Satoh T. et al, 「Bifidobacterium breve prevents necrotising enterocolitis by suppressing inflammatory responses in a preterm rat model.」. Benef Microbes. 30:1-8, (2015)
  • Sugahara.H et al, 「Differences in folate production by bifidobacteria of different origins」. Biosci Microbiota Food Health. 34:4(2015)
  • Minami.J et al, 「Oral administration of Bifidobacterium breve B-3 modifies metabolic functions in adults with obese tendencies in a randomised controlled trial」. J Nutr Sci. 4:e17 (2015)
  • Odamaki.T et al, 「Comparative Genomics Revealed Genetic Diversity and Species/Strain-Level Differences in Carbohydrate Metabolism of Three Probiotic Bifidobacterial Species」. Int J Genomics. 2015:567809(2015)
  • Satoh T. et al, 「Effect of Bifidobacterium breve B-3 on skin photoaging induced by chronic UV irradiation in mice.」. Beneficial Microbes 6(4):497-504(2015)
  • Muto.M et al, 「Enumeration of Bifidobacterium in powdered milk products: effect of suspension buffer and development of selective enumeration media」, ミルクサイエンス 64(1): 15-23 (2015)
  • 佐藤拓海ら「ビフィズス菌BB536の摂取が高齢者の免疫・腸内環境に及ぼす影響」. Food Style 21 18(12): 83-86 (2014)
  • 米澤寿美子ら「「アトピー性皮膚炎」に寄せる ビフィズス菌含有乳酸菌飲料摂取による肌状態改善作用」, アレルギーの臨床 34(10): 872-875 (2014)
  • 岩淵紀介「ビフィズス菌の免疫調節作用とその作用機序に関する研究 <平成25年度日本ビフィズス菌センター研究奨励賞受賞>」, 腸内細菌学雑誌 28(4): 141-146 (2014)
  • Enomoto T. et al,「Effects of Bifidobacterial Supplementation to Pregnant Women and Infants in the Prevention of Allergy Development in Infants and on Fecal Microbiota」. Allergol Int 63(4): 575-585 (2014)
  • Igarashi H. et al, 「Effect of oral administration of metronidazole or prednisolone on fecal microbiota in dogs.」. PLoS One. 2014 Sep 17;9(9):e107909.
  • 清水金忠「腸内細菌・プロバイオティクスと健康」, 和歌山保険医新聞 (419):3 2012.10.15
  • Iwabuchi N. et al, 「Immunomodulating and anti-infective effects of a novel strain of Lactobacillus paracasei that strongly induces interleukin-12」. FEMS Immunol Med Microbiol 66(2):230-239 (2012)
  • Odamaki T. et al, 「Effect of the oral intake of yogurt containing Bifidobacterium longum BB536 on the cell numbers of enterotoxigenic Bacteroides fragilis in microbiota.」. Anaerobe 18(1): 14-18 (2012)
  • Fujie H. et al, 「Toll-like receptor-2-activating bifidobacteria strains differentially regulate inflammatory cytokines in the porcine intestinal epithelial cell culture system: finding new anti-inflammatory immunobiotics.」. FEMS Immunol Med Microbiol 63(1): 129-139 (2011)
  • 近藤しずき「最近話題の脂肪酸に強くなる:腸内細菌との関係は?-腸内細菌叢が変わると血中脂質はよくなりますか?」, 肥満と糖尿病 10(6): 831-833 (2011)
  • Iwabuchi.N et al, 「Oral Administration of Bifidobacterium longum Ameliorates Influenza Virus Infection in Mice」. Biological & Pharmaceutical Bulletin 34(8): 1352-1355 (2011)
  • Odamaki T. et al, 「A one step genotypic identification of Lactococcus lactis subspecies at the species/strain levels.」. Syst Appl Microbiol 34(6): 429-434 (2011)
  • Odamaki T. et al, 「Novel multiplex polymerase chain reaction primer set for identification of Lactococcus species.」. Lett Appl Microbiol 52(5): 491-496 (2011)
  • Matsumoto T. et al, 「Oral administration of Bifidobacterium longum prevents gut-derived Pseudomonas aeruginosa sepsis in mice」. J Appl Microbiol, 104(3): 672-80 (2008)
  • Kabeir BM. et al, 「Safety evaluation of Bifidobacterium pseudocatenulatum G4 as assessed in BALB/c mice」. Lett Appl Microbiol, 46: 32-7 (2008)
  • Odamaki T. et al, 「Influence of Bifidobacterium longum BB536 intake on faecal microbiota in individuals with Japanese cedar pollinosis during the pollen season」. J Med Microbiol, 56: 1301-8 (2007)
  • Iwabuchi N. et al, 「In vitro Th1 cytokine-independent th2 suppressive effects of bifidobacteria」. Microbiol Immunol, 51(7): 649-60 (2007)
  • Xiao JZ. et al, 「Clinical efficacy of probiotic Bifidobacterium longum for the treatment of symptoms of Japanese cedar pollen allergy in subjects evaluated in an environmental exposure unit」. Allergology International, 56(1): 67-75 (2007)
  • Xiao JZ. et al, 「Changes in plasma TARC levels during Japanese cedar pollen season and relationships with symptom development」. Int Arch Allergy Immunol, 144(2): 123-127 (2007)
  • Odamaki T. et al, 「Fluctuation of fecal microbiota in individuals with Japanese cedar pollinosis during the pollen season and influence of probiotic intake」. J Investig Allergol Clin Immunol, 17(2): 92-100 (2007)
  • Sairanen U. et al, 「The effect of probiotic fermented milk and inulin on the functions and microecology of the intestine」. J Dairy Res, 74(3): 367-373 (2007)
  • Puccio G. et al, 「Clinical evaluation of a new starter formula for infants containing live Bifidobacterium longum BL999 and prebiotics」. Nutrition, 23: 1-8 (2007)
  • 清水(肖)金忠ら, 「Bifidobacterium longum BB536含有ドリンクタイプヨーグルト摂取による便秘傾向健常者の排便回数および排便性状に及ぼす影響」. Jpn.J. Lactic Acid Bact, 18(1): 31-36 (2007)
  • Kabeir BM. et al, 「Growth of Bifidobacterium longum BB536 in medida (fermented cereal porridge) and their survival during refrigerated storage」. Lett Appl Microbiol. 41: 125-31 (2005)
  • 石関しのぶら, 低出生体重児のビフィズス菌投与による腸内細菌叢の検討 -3種ビフィズス菌での効果-. 日本小児科学会雑誌 108: 283 (2004)
  • 佐藤弥生ら, 早産児に対するビフィズス菌投与効果について. 日本新生児学会雑誌 39(2): 247 (2003)
  • 服部和裕ら, アトピー性皮膚炎患児に対するビフィズス菌末の投与が児の腸内細菌叢とアレルギー症状に与える影響の検討. アレルギー 52(1): 20-30 (2003)
  • Zsivkovits M. et al, 「Prevention of heterocyclic amine-induced DNA damage in colon and liver of rats by different Lactobacillus strains」. Carcinogenesis, 24: 1913-1918 (2003)
  • Namba K. et al, 「Inhibitory effects of Bifidobacterium longum on enterohemorrhagic Escherichia coli O157:H7」. Bioscience Microflora, 22(3) : 85-91 (2003)
  • 八重島智子ら, 「Bifidobacterium longum BB536を含む非発酵乳酸菌飲料の排便回数および便性状に及ぼす影響」. 健康・栄養食品研究、4(2) : 1-6 (2001)
  • Fandi KG. et al, 「Purification and N-terminal amino acid sequence of fructose-6-phosphate phosphoketolase from Bifidobacterium longum BB536」. Lett Appl Microbiol. 32(4):235-9 (2001)
  • Ogata T. et al, 「Effect of Bifidobacterium longum BB536 yogurt administration on the intestinal environment of healthy adults.」. Microbial Ecology in Health and Disease, 11: 41-46 (1999)
  • 八重島智子ら, 「Bifidobacterium longum BB536含有加糖ヨーグルトの排便回数および排便性状に対する影響」. 健康・栄養食品研究、1(3/4) : 29-34 (1998)
  • Yaeshima T. et al, 「Effect of yogurt containing Bifidobacterium longum BB536 on the intestinal environment, fecal characteristics and defecation frequency.」. Bioscience Microflora, 16: 73-77 (1997)
  • Singh J. et al, 「Bifidobacterium longum, a lactic acid-producing intestinal bacterium inhibits colon cancer and modulates the intermediate biomarkers of colon carcinogenesis」. Carcinogenesis, 18: 833-841(1997)
  • Ogata T. et al, 「Effect of Bifidobacterium longum BB536 administration on the intestinal environment, defecation frequency and fecal characteristics of human volunteers.」. Bioscience Microflora, 16 : 53-58 (1997)
  • Challa A. et al, 「Bifidobacterium longum and lactulose suppress azoxymethane-induced colonic aberrant crypt foci in rats」. Carcinogenesis, 18: 517-521 (1997)
  • Tahri K. et al, 「Effects of three strains of bifidobacteria on cholesterol」. Lett Appl Microbiol 21: 149-151 (1995)
  • Grill JP. et al, 「Effect of bifidobacteria on nitrites and nitrosamines」. Lett Appl Microbiol 20: 328-330 (1995)
  • Grill JP. et al, 「Characterization of fructose 6 phosphate phosphoketolases purified from Bifidobacterium species」. Current Microbiology, 31: 49-54 (1995)
  • Grill JP. et al, 「Bifidobacteria and probiotic effects: action of Bifidobacterium species on conjugated bile salts」. Current Microbiology, 31: 23-27 (1995)
  • Grill JP. et al, 「Purification and Characterization of Conjugated Bile Salt Hydrolase from Bifidobacterium longum BB536.」. Appl Environ Microbiol. 61(7): 2577-2582 (1995)
  • Crociani J. et al, 「Adhesion of different bifidobacteria strains to human enterocyte-like Caco-2 cells and comparison with in vivo study」. Lett Appl Microbiol 21:146-148 (1995)
  • Araya-Kojima T. et al, 「Inhibitory effects of Bifidobacterium longum BB536 on harmful intestinal bacteria」. Bifidobacteria Microflora, 14(2) : 59-66 (1995)
  • 秋山和範ら, 「超未熟児におけるビフィズス菌の効果―Bifidobacterium breve投与による腸内細菌叢の変化」. 日本新生児学会雑誌、 30(1) : 130-137 (1994)
  • 秋山和範ら, 「超未熟児におけるビフィズス菌の効果:Bifidobacterium longum投与による腸内フローラの変化(Bifidobacterium breveとの比較)」. 日本新生児学会雑誌、 30(2): 257-263 (1994)
  • Sekine K. et al, 「Comparison of the TNF-αlevels induced by human-derived Bifidobacterium longum and rat-derived Bifidobacterium animalis in mouse peritoneal cells」. Bifidobacteria Microflora, 13(2): 79-89 (1994)
  • Orrhage K. et al, 「Effect of supplements with Bifidobacterium longum and Lactobacillus acidophilus on the intestinal microbiota during administration of clindamycin」. Microbiol Ecology Health & Disease, 7:17-25 (1994)
  • Kulkarni N and Reddy BS., 「Inhibitory effect of Bifidobacterium longum cultures on the Azoxymethane-induced aberrant crypt foci formation and fecal bacterialβ-glucuronidase」. Proc Soc Exp Biol Med, 207: 278-283 (1994)
  • 五十嵐 稔ら, 「ビフィズス菌及びラクチュロースの卵巣摘出骨粗鬆症モデルラットの大腿骨に対する骨強度増強効果」. ビフィズス、(2): 139-147 (1994)
  • Reddy BS and Rivenson A., 「Inhibitory effect of Bifidobacterium longum on colon, mammary and liver carcinogenesis induced by 2-amino-3-methylimidazo [4,5-f ] quinoline, a food mutagen」. Cancer Research, 53: 3914-3918 (1993)
  • Ballongue J. et al, 「Action sur la flore intestinale de laits fermentes au Bifidobacterium」. Lait, 73: 249-256 (1993)
  • Bennet R. et al, 「Transient colonization of the gut of newborn infants by orally administered bifidobacteria and lactobacilli」. Acta Paediatr, 81: 784-787 (1992)
  • Yamazaki S. et al, 「Immune response of Bifidobacterium-monoassociated mice」. Bifidobacteria Microflora, 10(1): 19-31 (1991)
  • Tomoda T. et al, 「Effect of yogurt and yogurt supplemented with Bifidobacterium and/or lactulose in healthy persons: a comparative study」. Bifidobacteria Microflora, 10(2): 123-130 (1991)
  • 友田恒典ら, 「健常者に対するBifidus菌含有ヨーグルト投与経験」. ビフィズス、4: 21-24 (1990)
  • Tomoda T. et al, 「Intestinal Candida overgrowth and Candida infection in patients with leukemia: effect of Bifidobacterium administration」. Bifidobacteria Microflora, 7(2): 71-74 (1988)
  • 陰山 克ら, 「Bifidus菌含有製品の経口投与の比較検討」. 医学と生物学、115(2) : 65-68 (1987)
  • Colombel JF. et al, 「Yogurt with Bifidobacterium longum reduces erythromycin-induced gastrointestinal effects」. The Lancet, II (8549): 43 (1987)
  • Ueda K. et al, 「Immunity provided by colonized enteric bacteria」. Bifidobacteria Microflora, 5(1): 67-72 (1986)
  • 関根勇夫ら, 「ビフィズス菌含有TM-1 milkの末梢血白血球化学発光、ならびに赤血球MCVに及ぼす影響―ビフィズス菌によるマクロファージの活性化」. 治療学、14(5): 691-695 (1985)
  • 海老沢悦子ら, 「産婦人科入院患者へのビフィズス菌入りヨーグルト"ラ・サンテ"の使用経験」. 臨床栄養、 66(7): 805-810 (1985)
  • Yamazaki S. et al, 「Immunological responses to monoassociated Bifidobacterium longum and their relation to prevention of bacterial invasion」. Immunology, 56: 43-50 (1985)
  • Kageyama T. et al, 「The effect of Bifidobacterium administration in patients with leukemia」. Bioscience Microflora, 3(1): 29-33 (1984)
  • Yamazaki S. et al, 「Protective effect of Bifidobacterium-monoassociation against lethal activity of Escherichia coli」. Bifidobacteria Microflora, 1(1) : 55-59 (1982)
  • 友田恒典ら, 「抗癌剤、免疫抑制剤投与時の少数常住腸内細菌の変動」. 医学と生物学、103(1): 45-49 (1981)
  • 百瀬寛資ら, 「Bifidobacterium longum BB-536の毒性試験」. 応用薬理、 17(5): 881-887 (1979)
  • 関 増爾ら, 「ビフィダスミルクによる高齢者の排便回数および糞便内ビフィダス菌数におよぼす影響」. 栄養と食糧、31(4): 379-387 (1978)